Co-inhibition of
Plasmodium falciparum
S-adenosylmethionine decarboxylase/ornithine
decarboxylase reveals perturbation-specific
compensatory mechanisms by transcriptome,
proteome and metabolome analyses
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primary data clusters
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Below are exploratory clusters produced by unsupervised hierarchical data clustering. Cluster tightness is indicated with correlation values in parentheses and all files are in .png format.
Clusters of all data
Differential decay rate cluster (correlation = 0.96)
LDC cluster (correlation = 0.91)
OAT and AdoMet-dependent methyltransferase cluster (correlation = 0.92)
PfAdoMetDC/ODC and other polyamine pathway transcripts cluster (correlation = 0.85)
Polyamine and methionine metabolism-biased cluster (Top correlation = 0.95 Bottom correlation = 0.75)
Ribosomal components cluster (correlation = 0.96)
Clusters against UTt
1
(relative t
0
)
Genes off arrest cluster (correlation = 0.936)
Genes on arrest cluster (correlation = 0.944)
PfAdoMetDC/ODC and other polyamine pathway transcripts cluster (correlation = 0.896)
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Last updated: 1 September 2008