Viro-Genome Browser

Comparative genomics reveal the genetic basis of phenotypic variation between different strains of alphaherpesvirus.

Alpha-herpesviruses infect the host's nervous system. Distinct virus strains display phenotypic differences in neurons, such as different rates of spread from neuron to neuron. The Enquist lab website has more information on HSV-1 and PRV biology.

Click on one of the images below to select strains of the corresponding genome to view in the GBrowse browser. Tutorial available here.

Herpes simplex virus 1 (HSV-1) Genomes

Viro-Genome front page image

Sequence variability in clinical and lab isolates of HSV1 reveals new mutations.

Szpara et al. (2010) J Virol 84(10):5303-5313.

Pseudorabies virus (PRV) (Suid herpesvirus (SuHV-1)) Genomes

Viro-Genome front page image

A wide extent of inter-strain diversity in virulent and vaccine strains of alphaherpesviruses.

Szpara et al. (2011) PLoS Pathog 7(10): e1002282

Supplementary Data website

Images above courtesy of Pat Card and Moriah Szpara.